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To manufacture medical devices (or any measuring/diagnostic devices), we need to account for hardware variability in addition to the biological variations of the sample.

We could represent the problem as consisting of three parts: software, hardware, and calibration.

Calibration Transfer Task

First of all, one needs to make sure that two assumptions are true:

Calibration Transfer Assumptions

Then, one needs to develop a Calibration Transfer Method, such that when applied together with regression coefficients to any of the "slave" instruments, the latter gave true diagnostics independent of hardware, sofware, or external conditions:

Calibration Transfer Solution

Work was done while at Argose Inc.